Turkish vaccine Covid-19: “innovative and unique in the world”
Turkey presents vaccine projects.
President Erdogan wants to accelerate vaccination in his country but also provide doses to “the whole of humanity”.
In recent days, in Ankara, Health Minister Fahrettin Koca is on all fronts. The number of Covid-19 infections is increasing. The government announced a weekend lockdown and the maintenance of the curfew. To counterbalance, the Turkish government is trying to give some hope. This week, he shared extensively on national scientific advances in vaccines.
If Turkey uses American Pfizer and Chinese Sinovac vaccines now, then the state strongly supports “local” researchers. Tübitak (the scientific and technological research council of turkey) oversees several projects are. Two of them seem promising and are subject to media threshing orchestrated by the government.
The vaccine “pseudo-viral particles”
Mayda and Ihsan Gürsel, a couple of scientists, is developing a Turkish vaccine Covid-19 based on the technology of “pseudo-viral particles” in Ankara. The Turkish Minister of Industry Mustafa Varank, welcomed Wednesday “a very innovative method”. The serum has just joined the list of WHO. Among the 84 clinical trial vaccine candidates identified by the global organization, only three other laboratories explore this technology: a Canadian company (Medicago), an American (VBI vaccine) and an Indian institute. “We use a ghost of the viral particle. Without anything in it, we totally empty of its RNA “Decrypt Stéphane Paul, an immunologist at the Saint-Etienne University Hospital.
The latter, by assemblage, form a micro-bubble. When injected into the body, it really mimes the infection by the virus. This Scientific Council member on Vaccines explains that the structure of the Spike protein is very similar”. The formula has many benefits against CVIV-19. First, “it’s very immunogenic, so you don’t necessarily need an adjuvant,” says the doctor. Secondly, it can be multivalent, i.e. the same injection works against several variants. Finally, it is less subject to side effects than vaccines in Adenovirus. Turkey indicates that it will design with an unveiled industrial partner, which could “provide up to” 50 million doses “.
The “intranasal” Turkish vaccine Covid-19
Turkey’s Health Minister on Wednesday unveiled the outlines of another vaccine against Covid-19, which he describes as”unique in the world”. We inject the dose like a nasal spray against colds. “It’s an exciting approach,” admits Stéphane Paul. He says that” not all countries have mastered this.” Vaccinating in the nose offers the advantage of providing rapid immunity locally to avoid nasopharyngeal transmission. “It also requires a smaller amount of vaccine, about 1 / 10th of the dose needed intramuscularly,” adds the specialist.
When children need to be vaccinated, it can also allow for greater adoption, avoiding the “fear of the needle”. At present, in the world, this technology carries a share of risk if we control it poorly. “It has always been hampered in the clinical development because there have been cases of facial paralysis of Bell. The barrier to the brain is very close: there may be a passage of the vaccine at the encephalic level, ” the immunologist says. Two hundred fifty million doses could be produced, according to the government agency Anadolu.
Turkish vaccine Covid-19: “A gift for humanity ?»
These projects could help speed up vaccination in Turkey, which is somewhat skidding. As of 1 April, 10.92% of the population had received at least one dose. For example, this is less than some European countries… At a UN videoconference meeting, the Turkish president stressed that he would make the doses “available to the whole of humanity, once the work is completed.
This confirms his strategy which consisted until now in “building diplomatic bridges between countries that produce vaccines and countries that have problems of access to the vaccine”, as the Minister of Health recalled at a press conference. Erdogan regularly criticizes the difficulties of access to doses for developing countries. “He wants to register as a leader of non-aligned countries, against the great powers,” explains Jean-François Perouse, researcher and co-author of the book Erdogan: new father of Turkey?. This vaccine case is another opportunity for him to use this anti-monopoly rhetoric.
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